PoplarV1, Main, Exploration, bibRecord, 000489

Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces.

Identifieur interne : 000489 ( Main/Exploration ); précédent : 000488; suivant : 000490

Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces.

Auteurs : Sai Venkatesh Pingali [États-Unis] ; Micholas Dean Smith [États-Unis] ; Shih-Hsien Liu [États-Unis] ; Takat B. Rawal [États-Unis] ; Yunqiao Pu [États-Unis] ; Riddhi Shah [États-Unis] ; Barbara R. Evans [États-Unis] ; Volker S. Urban [États-Unis] ; Brian H. Davison [États-Unis] ; Charles M. Cai [États-Unis] ; Arthur J. Ragauskas [États-Unis] ; Hugh M. O'Neill [États-Unis] ; Jeremy C. Smith [États-Unis] ; Loukas Petridis [États-Unis]

Source :

Proceedings of the National Academy of Sciences of the United States of America [ 1091-6490 ] ; 2020.

RBID : pubmed:32636260

Descripteurs français

KwdFr :
- Biomasse (MeSH), Biotechnologie (méthodes), Bois (composition chimique), Cellulase (métabolisme), Furanes (composition chimique), Gluconacetobacter xylinus (enzymologie), Hydrolyse (MeSH), Lignine (composition chimique), Lignine (métabolisme), Populus (composition chimique), Protéines bactériennes (métabolisme), Solvants (composition chimique), Tensioactifs (composition chimique).
MESH :
- composition chimique : Bois, Furanes, Lignine, Populus, Solvants, Tensioactifs.
- enzymologie : Gluconacetobacter xylinus.
- métabolisme : Cellulase, Lignine, Protéines bactériennes.
- méthodes : Biotechnologie.
- Biomasse, Hydrolyse.

English descriptors

KwdEn :
- Bacterial Proteins (metabolism), Biomass (MeSH), Biotechnology (methods), Cellulase (metabolism), Furans (chemistry), Gluconacetobacter xylinus (enzymology), Hydrolysis (MeSH), Lignin (chemistry), Lignin (metabolism), Populus (chemistry), Solvents (chemistry), Surface-Active Agents (chemistry), Wood (chemistry).
MESH :
- chemical , chemistry : Furans, Lignin, Solvents, Surface-Active Agents.
- chemical , metabolism : Bacterial Proteins, Cellulase, Lignin.
- chemistry : Populus, Wood.
- enzymology : Gluconacetobacter xylinus.
- methods : Biotechnology.
- Biomass, Hydrolysis.

Abstract

A particularly promising approach to deconstructing and fractionating lignocellulosic biomass to produce green renewable fuels and high-value chemicals pretreats the biomass with organic solvents in aqueous solution. Here, neutron scattering and molecular-dynamics simulations reveal the temperature-dependent morphological changes in poplar wood biomass during tetrahydrofuran (THF):water pretreatment and provide a mechanism by which the solvent components drive efficient biomass breakdown. Whereas lignin dissociates over a wide temperature range (>25 °C) cellulose disruption occurs only above 150 °C. Neutron scattering with contrast variation provides direct evidence for the formation of THF-rich nanoclusters (R_g ∼ 0.5 nm) on the nonpolar cellulose surfaces and on hydrophobic lignin, and equivalent water-rich nanoclusters on polar cellulose surfaces. The disassembly of the amphiphilic biomass is thus enabled through the local demixing of highly functional cosolvents, THF and water, which preferentially solvate specific biomass surfaces so as to match the local solute polarity. A multiscale description of the efficiency of THF:water pretreatment is provided: matching polarity at the atomic scale prevents lignin aggregation and disrupts cellulose, leading to improvements in deconstruction at the macroscopic scale.

DOI: 10.1073/pnas.1922883117
PubMed: 32636260
PubMed Central: PMC7382264

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000207
to stream Main, to step Curation: 000207

Le document en format XML

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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
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<author><name sortKey="Pingali, Sai Venkatesh" sort="Pingali, Sai Venkatesh" uniqKey="Pingali S" first="Sai Venkatesh" last="Pingali">Sai Venkatesh Pingali</name>
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<author><name sortKey="Rawal, Takat B" sort="Rawal, Takat B" uniqKey="Rawal T" first="Takat B" last="Rawal">Takat B. Rawal</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
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<author><name sortKey="Pu, Yunqiao" sort="Pu, Yunqiao" uniqKey="Pu Y" first="Yunqiao" last="Pu">Yunqiao Pu</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
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<author><name sortKey="Shah, Riddhi" sort="Shah, Riddhi" uniqKey="Shah R" first="Riddhi" last="Shah">Riddhi Shah</name>
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<author><name sortKey="Evans, Barbara R" sort="Evans, Barbara R" uniqKey="Evans B" first="Barbara R" last="Evans">Barbara R. Evans</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge</wicri:cityArea>
</affiliation>
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<author><name sortKey="Urban, Volker S" sort="Urban, Volker S" uniqKey="Urban V" first="Volker S" last="Urban">Volker S. Urban</name>
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<author><name sortKey="Davison, Brian H" sort="Davison, Brian H" uniqKey="Davison B" first="Brian H" last="Davison">Brian H. Davison</name>
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</placeName>
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</affiliation>
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<author><name sortKey="Cai, Charles M" sort="Cai, Charles M" uniqKey="Cai C" first="Charles M" last="Cai">Charles M. Cai</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Center for Environmental Research and Technology, Bourns College of Engineering, University of California, Riverside</wicri:cityArea>
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<affiliation wicri:level="2"><nlm:affiliation>Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
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</affiliation>
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<author><name sortKey="Ragauskas, Arthur J" sort="Ragauskas, Arthur J" uniqKey="Ragauskas A" first="Arthur J" last="Ragauskas">Arthur J. Ragauskas</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
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<author><name sortKey="O Neill, Hugh M" sort="O Neill, Hugh M" uniqKey="O Neill H" first="Hugh M" last="O'Neill">Hugh M. O'Neill</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
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</affiliation>
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<author><name sortKey="Smith, Jeremy C" sort="Smith, Jeremy C" uniqKey="Smith J" first="Jeremy C" last="Smith">Jeremy C. Smith</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge</wicri:cityArea>
</affiliation>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Petridis, Loukas" sort="Petridis, Loukas" uniqKey="Petridis L" first="Loukas" last="Petridis">Loukas Petridis</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
<wicri:cityArea>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Tennessee</region>
</placeName>
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</affiliation>
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<series><title level="j">Proceedings of the National Academy of Sciences of the United States of America</title>
<idno type="eISSN">1091-6490</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bacterial Proteins (metabolism)</term>
<term>Biomass (MeSH)</term>
<term>Biotechnology (methods)</term>
<term>Cellulase (metabolism)</term>
<term>Furans (chemistry)</term>
<term>Gluconacetobacter xylinus (enzymology)</term>
<term>Hydrolysis (MeSH)</term>
<term>Lignin (chemistry)</term>
<term>Lignin (metabolism)</term>
<term>Populus (chemistry)</term>
<term>Solvents (chemistry)</term>
<term>Surface-Active Agents (chemistry)</term>
<term>Wood (chemistry)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Biomasse (MeSH)</term>
<term>Biotechnologie (méthodes)</term>
<term>Bois (composition chimique)</term>
<term>Cellulase (métabolisme)</term>
<term>Furanes (composition chimique)</term>
<term>Gluconacetobacter xylinus (enzymologie)</term>
<term>Hydrolyse (MeSH)</term>
<term>Lignine (composition chimique)</term>
<term>Lignine (métabolisme)</term>
<term>Populus (composition chimique)</term>
<term>Protéines bactériennes (métabolisme)</term>
<term>Solvants (composition chimique)</term>
<term>Tensioactifs (composition chimique)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Furans</term>
<term>Lignin</term>
<term>Solvents</term>
<term>Surface-Active Agents</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Bacterial Proteins</term>
<term>Cellulase</term>
<term>Lignin</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Populus</term>
<term>Wood</term>
</keywords>
<keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Bois</term>
<term>Furanes</term>
<term>Lignine</term>
<term>Populus</term>
<term>Solvants</term>
<term>Tensioactifs</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Gluconacetobacter xylinus</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Gluconacetobacter xylinus</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Biotechnology</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cellulase</term>
<term>Lignine</term>
<term>Protéines bactériennes</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Biotechnologie</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Biomass</term>
<term>Hydrolysis</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Biomasse</term>
<term>Hydrolyse</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A particularly promising approach to deconstructing and fractionating lignocellulosic biomass to produce green renewable fuels and high-value chemicals pretreats the biomass with organic solvents in aqueous solution. Here, neutron scattering and molecular-dynamics simulations reveal the temperature-dependent morphological changes in poplar wood biomass during tetrahydrofuran (THF):water pretreatment and provide a mechanism by which the solvent components drive efficient biomass breakdown. Whereas lignin dissociates over a wide temperature range (>25 °C) cellulose disruption occurs only above 150 °C. Neutron scattering with contrast variation provides direct evidence for the formation of THF-rich nanoclusters (R<sub>g</sub>
 ∼ 0.5 nm) on the nonpolar cellulose surfaces and on hydrophobic lignin, and equivalent water-rich nanoclusters on polar cellulose surfaces. The disassembly of the amphiphilic biomass is thus enabled through the local demixing of highly functional cosolvents, THF and water, which preferentially solvate specific biomass surfaces so as to match the local solute polarity. A multiscale description of the efficiency of THF:water pretreatment is provided: matching polarity at the atomic scale prevents lignin aggregation and disrupts cellulose, leading to improvements in deconstruction at the macroscopic scale.</div>
</front>
</TEI>
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<DateCompleted><Year>2020</Year>
<Month>09</Month>
<Day>07</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1091-6490</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>117</Volume>
<Issue>29</Issue>
<PubDate><Year>2020</Year>
<Month>07</Month>
<Day>21</Day>
</PubDate>
</JournalIssue>
<Title>Proceedings of the National Academy of Sciences of the United States of America</Title>
<ISOAbbreviation>Proc Natl Acad Sci U S A</ISOAbbreviation>
</Journal>
<ArticleTitle>Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces.</ArticleTitle>
<Pagination><MedlinePgn>16776-16781</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1073/pnas.1922883117</ELocationID>
<Abstract><AbstractText>A particularly promising approach to deconstructing and fractionating lignocellulosic biomass to produce green renewable fuels and high-value chemicals pretreats the biomass with organic solvents in aqueous solution. Here, neutron scattering and molecular-dynamics simulations reveal the temperature-dependent morphological changes in poplar wood biomass during tetrahydrofuran (THF):water pretreatment and provide a mechanism by which the solvent components drive efficient biomass breakdown. Whereas lignin dissociates over a wide temperature range (>25 °C) cellulose disruption occurs only above 150 °C. Neutron scattering with contrast variation provides direct evidence for the formation of THF-rich nanoclusters (R<sub>g</sub>
 ∼ 0.5 nm) on the nonpolar cellulose surfaces and on hydrophobic lignin, and equivalent water-rich nanoclusters on polar cellulose surfaces. The disassembly of the amphiphilic biomass is thus enabled through the local demixing of highly functional cosolvents, THF and water, which preferentially solvate specific biomass surfaces so as to match the local solute polarity. A multiscale description of the efficiency of THF:water pretreatment is provided: matching polarity at the atomic scale prevents lignin aggregation and disrupts cellulose, leading to improvements in deconstruction at the macroscopic scale.</AbstractText>
<CopyrightInformation>Copyright © 2020 the Author(s). Published by PNAS.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pingali</LastName>
<ForeName>Sai Venkatesh</ForeName>
<Initials>SV</Initials>
<AffiliationInfo><Affiliation>Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, ORNL TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>Micholas Dean</ForeName>
<Initials>MD</Initials>
<AffiliationInfo><Affiliation>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Shih-Hsien</ForeName>
<Initials>SH</Initials>
<AffiliationInfo><Affiliation>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rawal</LastName>
<ForeName>Takat B</ForeName>
<Initials>TB</Initials>
<Identifier Source="ORCID">0000-0003-3191-7770</Identifier>
<AffiliationInfo><Affiliation>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pu</LastName>
<ForeName>Yunqiao</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Shah</LastName>
<ForeName>Riddhi</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, ORNL TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Evans</LastName>
<ForeName>Barbara R</ForeName>
<Initials>BR</Initials>
<Identifier Source="ORCID">0000-0002-2574-2567</Identifier>
<AffiliationInfo><Affiliation>Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Urban</LastName>
<ForeName>Volker S</ForeName>
<Initials>VS</Initials>
<AffiliationInfo><Affiliation>Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, ORNL TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Davison</LastName>
<ForeName>Brian H</ForeName>
<Initials>BH</Initials>
<Identifier Source="ORCID">0000-0002-7408-3609</Identifier>
<AffiliationInfo><Affiliation>Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cai</LastName>
<ForeName>Charles M</ForeName>
<Initials>CM</Initials>
<Identifier Source="ORCID">0000-0002-5047-0815</Identifier>
<AffiliationInfo><Affiliation>Center for Environmental Research and Technology, Bourns College of Engineering, University of California, Riverside, CA 92521.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ragauskas</LastName>
<ForeName>Arthur J</ForeName>
<Initials>AJ</Initials>
<Identifier Source="ORCID">0000-0002-3536-554X</Identifier>
<AffiliationInfo><Affiliation>Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>O'Neill</LastName>
<ForeName>Hugh M</ForeName>
<Initials>HM</Initials>
<AffiliationInfo><Affiliation>Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, ORNL TN 37830.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>Jeremy C</ForeName>
<Initials>JC</Initials>
<AffiliationInfo><Affiliation>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge, TN 37830.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Petridis</LastName>
<ForeName>Loukas</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge, TN 37830; petridisl@ornl.gov.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>07</Month>
<Day>07</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Proc Natl Acad Sci U S A</MedlineTA>
<NlmUniqueID>7505876</NlmUniqueID>
<ISSNLinking>0027-8424</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D001426">Bacterial Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D005663">Furans</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012997">Solvents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D013501">Surface-Active Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>3N8FZZ6PY4</RegistryNumber>
<NameOfSubstance UI="C018674">tetrahydrofuran</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>9005-53-2</RegistryNumber>
<NameOfSubstance UI="D008031">Lignin</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.2.1.4</RegistryNumber>
<NameOfSubstance UI="D002480">Cellulase</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001426" MajorTopicYN="N">Bacterial Proteins</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018533" MajorTopicYN="N">Biomass</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001709" MajorTopicYN="N">Biotechnology</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002480" MajorTopicYN="N">Cellulase</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005663" MajorTopicYN="N">Furans</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D041822" MajorTopicYN="N">Gluconacetobacter xylinus</DescriptorName>
<QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006868" MajorTopicYN="N">Hydrolysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008031" MajorTopicYN="N">Lignin</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012997" MajorTopicYN="N">Solvents</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013501" MajorTopicYN="N">Surface-Active Agents</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014934" MajorTopicYN="N">Wood</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">biomass</Keyword>
<Keyword MajorTopicYN="Y">pretreatment</Keyword>
<Keyword MajorTopicYN="Y">solvents</Keyword>
</KeywordList>
<CoiStatement>The authors declare no competing interest.</CoiStatement>
</MedlineCitation>
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<affiliations><list><country><li>États-Unis</li>
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Serveur d'exploration sur le peuplier

Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces.

Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces.

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